CD57
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P |
|---|---|
| Primary Accession | Q9P2W7 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 334E2F5 |
| Calculated MW | 38256 Da |
| Gene ID | 27087 |
|---|---|
| Gene Name | B3GAT1 (HGNC:921) |
| Other Names | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, 2.4.1.135, UDP-GlcUA:glycoprotein beta-1, 3-glucuronyltransferase, GlcUAT-P, B3GAT1 (HGNC:921), GLCATP |
| Dilution | IHC-P~~Ready-to-use |
| Storage | Maintain refrigerated at 2-8°C |
| Precautions | CD57 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | B3GAT1 (HGNC:921) |
|---|---|
| Synonyms | GLCATP |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Cellular Location | Isoform 1: Golgi apparatus membrane {ECO:0000250|UniProtKB:O35789}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O35789}. Secreted {ECO:0000250|UniProtKB:O35789} |
| Tissue Location | Mainly expressed in the brain. |

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