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NKX3.1

Rabbit Monoclonal antibody(Mab)

     
  • IHC-P - NKX3.1 AD80224-010
    Prostate cancer
    detail
  • IHC - NKX3.1 AD80224-010
    Immunohistochemical analysis of paraffin-embedded prostatic cancer tissue using AD80224 performed on the Abcarta® FAIP-30 Fully automated IHC platform.Tissue was fixed with formaldehyde at room temperature, antigen retrieval was by heat mediation with a EDTA buffer (pH9. 0). Samples were incubated with primary antibody(Ready-to-use) for 15 min at room temperature. AmpSeeTM Detection Systems(Abcepta:AR005) was used as the secondary antibody.
    detail
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Product info
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession Q99801
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names 787G3C0
Calculated MW 26350 Da
Additional info
Gene ID 4824
Gene Name NKX3-1
Other Names Homeobox protein Nkx-3.1, Homeobox protein NK-3 homolog A, NKX3-1 (HGNC:7838)
Dilution IHC-P~~Ready-to-use
IHC~~Ready-to-use
Storage This product is stored at 2-234 ℃, please use it within the expiration date.
Precautions NKX3.1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKX3-1 (HGNC:7838)
Synonyms NKX3.1, NKX3A
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:11137288}
Tissue Location Highly expressed in the prostate and, at a lower level, in the testis.
Research Areas
Citations (0)
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$ 127.00
$ 153.00
$ 182.00
Cat# AD80224-010
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