CD16
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| IHC-P |
|---|---|
| Primary Accession | P08637 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 526A1C6 |
| Calculated MW | 29089 Da |
| Gene ID | 2214 |
|---|---|
| Gene Name | FCGR3A |
| Other Names | Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A {ECO:0000303|PubMed:23006327} |
| Dilution | IHC-P~~Ready-to-use |
| Storage | Maintain refrigerated at 2-8°C |
| Precautions | CD16 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FCGR3A {ECO:0000303|PubMed:23006327} |
|---|---|
| Synonyms | CD16A, FCG3, FCGR3, IGFR3 |
| Function | Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein. Secreted. Note=Exists also as a soluble receptor |
| Tissue Location | Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts |

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