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uPAR Antibody
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC |
|---|---|
| Primary Accession | Q03405 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Clone Names | 745B3V1 |
| Calculated MW | 36978 Da |
| Gene ID | 5329 |
|---|---|
| Gene Name | PLAUR |
| Other Names | Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Monocyte activation antigen Mo3, CD87, PLAUR, MO3, UPAR |
| Storage | Maintain refrigerated at 2-8°C |
| Precautions | uPAR Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLAUR |
|---|---|
| Synonyms | MO3, UPAR |
| Function | Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| Cellular Location | Cell membrane. Cell projection, invadopodium membrane. Note=Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin-dependent manner Isoform 2: Secreted {ECO:0000250|UniProtKB:P49616} |
| Tissue Location | Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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Cat# AD80311-010
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