Goat Anti-APOBEC2 (aa12 - 26) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, E |
---|---|
Primary Accession | Q9Y235 |
Other Accession | NP_006780, 10930, 11811 (mouse), 301226 (rat) |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 25703 Da |
Gene ID | 10930 |
---|---|
Other Names | Probable C->U-editing enzyme APOBEC-2, 3.5.4.-, APOBEC2 |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-APOBEC2 (aa12 - 26) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | APOBEC2 |
---|---|
Function | Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. |
Tissue Location | Expressed exclusively in heart and skeletal muscle. |

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Provided below are standard protocols that you may find useful for product applications.
References
Microarray analysis of tonsils in immunoglobulin A nephropathy patients. Iio K, et al. Biochem Biophys Res Commun, 2010 Mar 19. PMID 20138841.
APOBEC deaminases-mutases with defensive roles for immunity. Prochnow C, et al. Sci China C Life Sci, 2009 Oct. PMID 19911124.
Gender differences in genetic risk profiles for cardiovascular disease. Silander K, et al. PLoS One, 2008. PMID 18974842.
The APOBEC-2 crystal structure and functional implications for the deaminase AID. Prochnow C, et al. Nature, 2007 Jan 25. PMID 17187054.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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