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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat Anti-PNPLA3 / Adiponutrin Antibody
Goat Anti-PNPLA3 / Adiponutrin Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | Q9NST1 |
| Other Accession | NP_473429, 80339, 116939 (mouse), 362972 (rat) |
| Reactivity | Human, Mouse |
| Predicted | Rat, Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 100ug/200ul |
| Isotype | IgG |
| Calculated MW | 52865 Da |
| Gene ID | 80339 |
|---|---|
| Other Names | Patatin-like phospholipase domain-containing protein 3, 3.1.1.3, Acylglycerol O-acyltransferase, 2.3.1.-, Adiponutrin, Calcium-independent phospholipase A2-epsilon, iPLA2-epsilon, PNPLA3, ADPN, C22orf20 |
| Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat Anti-PNPLA3 / Adiponutrin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLPL3 |
|---|---|
| Function | Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA (PubMed:22560221). Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides (PubMed:15364929, PubMed:20034933, PubMed:22560221). In vitro may express hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety (PubMed:21878620). However, the triacylglycerol hydrolase activity is controversial and may be very low (PubMed:22560221). Possesses phospholipase A2 activity (PubMed:15364929). |
| Cellular Location | Membrane; Single-pass type II membrane protein. Lipid droplet |
Research Areas
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$ 423.00
Cat# AF1845a
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