Goat Anti-XAB2 / HCNP Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IHC, E |
---|---|
Primary Accession | Q9HCS7 |
Other Accession | NP_064581, 56949 |
Reactivity | Human |
Predicted | Mouse, Rat, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 100010 Da |
Gene ID | 56949 |
---|---|
Other Names | Pre-mRNA-splicing factor SYF1, Protein HCNP, XPA-binding protein 2, XAB2, HCNP, KIAA1177, SYF1 |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-XAB2 / HCNP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | XAB2 |
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Synonyms | HCNP, KIAA1177, SYF1 |
Function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770). Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing (PubMed:10944529, PubMed:17981804). |
Cellular Location | Nucleus. Note=Detected in the splicing complex carrying pre-mRNA. {ECO:0000250|UniProtKB:Q99PK0} |

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Provided below are standard protocols that you may find useful for product applications.
References
Variation within DNA repair pathway genes and risk of multiple sclerosis. Briggs FB, et al. Am J Epidemiol, 2010 Jul 15. PMID 20522537.
Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair. Kuraoka I, et al. J Biol Chem, 2008 Jan 11. PMID 17981804.
Towards a proteome-scale map of the human protein-protein interaction network. Rual JF, et al. Nature, 2005 Oct 20. PMID 16189514.
Large-scale cDNA transfection screening for genes related to cancer development and progression. Wan D, et al. Proc Natl Acad Sci U S A, 2004 Nov 2. PMID 15498874.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

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