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XAB2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HCS7 |
| Other Accession | Q99PK0, Q9DCD2, NP_064581.2 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 100010 Da |
| Antigen Region | 450-479 aa |
| Gene ID | 56949 |
|---|---|
| Other Names | Pre-mRNA-splicing factor SYF1, Protein HCNP, XPA-binding protein 2, XAB2, HCNP, KIAA1177, SYF1 |
| Target/Specificity | This XAB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the Central region of human XAB2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | XAB2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | XAB2 |
|---|---|
| Synonyms | HCNP, KIAA1177, SYF1 |
| Function | Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28076346, PubMed:28502770). Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing (PubMed:10944529, PubMed:17981804). |
| Cellular Location | Nucleus. Note=Detected in the splicing complex carrying pre-mRNA. {ECO:0000250|UniProtKB:Q99PK0} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
References
Briggs, F.B., et al. Am. J. Epidemiol. (2010) In press :
Kuraoka, I., et al. J. Biol. Chem. 283(2):940-950(2008)
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Nakayama, M., et al. Genome Res. 12(11):1773-1784(2002)
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