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PSAP / MTCH1 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q9NZJ7 |
| Other Accession | NP_055156.1, 23787, 56462 (mouse) |
| Predicted | Human, Mouse, Rat, Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 41544 Da |
| Gene ID | 23787 |
|---|---|
| Other Names | Mitochondrial carrier homolog 1, Presenilin-associated protein, MTCH1, PSAP |
| Dilution | E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PSAP / MTCH1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MTCH1 {ECO:0000303|PubMed:36264797, ECO:0000312|HGNC:HGNC:17586} |
|---|---|
| Function | Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (PubMed:36264797). Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins (By similarity). Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). May play a role in apoptosis (PubMed:12377771). |
| Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed with a predominant expression in brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein. Xu X, Shi YC, Gao W, Mao G, Zhao G, Agrawal S, Chisolm GM, Sui D, Cui MZ. J Biol Chem. 2002 Dec 13;277(50):48913-22. Epub 2002 Oct 10. PMID: 12377771
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