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MTCH1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NZJ7 |
| Other Accession | Q791T5 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 41544 Da |
| Antigen Region | 151-177 aa |
| Gene ID | 23787 |
|---|---|
| Other Names | Mitochondrial carrier homolog 1, Presenilin-associated protein, MTCH1, PSAP |
| Target/Specificity | This MTCH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the Central region of human MTCH1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MTCH1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MTCH1 {ECO:0000303|PubMed:36264797, ECO:0000312|HGNC:HGNC:17586} |
|---|---|
| Function | Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (PubMed:36264797). Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins (By similarity). Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). May play a role in apoptosis (PubMed:12377771). |
| Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein |
| Tissue Location | Widely expressed with a predominant expression in brain. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Potential mitochondrial transporter. May play a role in apoptosis.
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$ 150.00
$ 385.00
Cat# AP20405c
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