MTCH1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9NZJ7 |
Other Accession | Q791T5 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 41544 Da |
Antigen Region | 151-177 aa |
Gene ID | 23787 |
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Other Names | Mitochondrial carrier homolog 1, Presenilin-associated protein, MTCH1, PSAP |
Target/Specificity | This MTCH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-177 amino acids from the Central region of human MTCH1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MTCH1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MTCH1 {ECO:0000303|PubMed:36264797, ECO:0000312|HGNC:HGNC:17586} |
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Function | Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane (PubMed:36264797). Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins (By similarity). Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). May play a role in apoptosis (PubMed:12377771). |
Cellular Location | Mitochondrion outer membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed with a predominant expression in brain. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Potential mitochondrial transporter. May play a role in apoptosis.
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