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Rhophilin 2 (Internal) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC, E |
|---|---|
| Primary Accession | Q8IUC4 |
| Other Accession | NP_149094.3, 85415 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 76993 Da |
| Gene ID | 85415 |
|---|---|
| Other Names | Rhophilin-2, 76 kDa RhoB effector protein, GTP-Rho-binding protein 2, p76RBE, RHPN2 |
| Dilution | IHC~~1:100~500 E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Rhophilin 2 (Internal) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RHPN2 |
|---|---|
| Function | Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. |
| Cellular Location | Cytoplasm, perinuclear region |
| Tissue Location | Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization. Peck JW, Oberst M, Bouker KB, Bowden E, Burbelo PD. J Biol Chem. 2002 Nov 15;277(46):43924-32. PMID: 12221077
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