Neurogenin 1 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| E |
|---|---|
| Primary Accession | Q92886 |
| Other Accession | NP_006152.2, 4762, 18014 (mouse), 29410 (rat) |
| Predicted | Human, Mouse, Rat, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 25718 Da |
| Gene ID | 4762 |
|---|---|
| Other Names | Neurogenin-1, NGN-1, Class A basic helix-loop-helix protein 6, bHLHa6, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, NeuroD3, NEUROG1, BHLHA6, NEUROD3, NGN, NGN1 |
| Dilution | E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Neurogenin 1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NEUROG1 |
|---|---|
| Synonyms | BHLHA6, NEUROD3, NGN, NGN1 |
| Function | Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity). |
| Cellular Location | Nucleus. |
| Tissue Location | Expression restricted to the embryonic nervous system |

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References
Association between the 5q31.1 gene neurogenin1 and schizophrenia. Fanous AH, Chen X, Wang X, Amdur RL, O'Neill FA, Walsh D, Kendler KS. Am J Med Genet B Neuropsychiatr Genet. 2007 Mar 5;144(2):207-14. PMID: 17044100
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