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NEUROG1 Antibody (monoclonal) (M06)
Mouse monoclonal antibody raised against a partial recombinant NEUROG1.
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- BACKGROUND
Application 
| WB, IF |
|---|---|
| Primary Accession | Q92886 |
| Other Accession | NM_006161 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a Kappa |
| Clone Names | 4A2 |
| Calculated MW | 25718 Da |
| Gene ID | 4762 |
|---|---|
| Other Names | Neurogenin-1, NGN-1, Class A basic helix-loop-helix protein 6, bHLHa6, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, NeuroD3, NEUROG1, BHLHA6, NEUROD3, NGN, NGN1 |
| Target/Specificity | NEUROG1 (NP_006152, 82 a.a. ~ 163 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | NEUROG1 Antibody (monoclonal) (M06) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
The basic helix-loop-helix region of human neurogenin 1 is a monomeric natively unfolded protein which forms a fuzzy complex upon DNA binding. Aguado-Llera D, et al. Biochemistry, 2010 Mar 2. PMID 20102160. Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized human neural stem cell line HB1.F3. Satoh J, et al. Cell Mol Neurobiol, 2010 Apr. PMID 19813087. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. Gratac簷s M, et al. Am J Med Genet B Neuropsychiatr Genet, 2009 Sep 5. PMID 19086053. Basic helix-loop-helix transcription factor NEUROG1 and schizophrenia: effects on illness susceptibility, MRI brain morphometry and cognitive abilities. Ho BC, et al. Schizophr Res, 2008 Dec. PMID 18799289. Association of autism with polymorphisms in the paired-like homeodomain transcription factor 1 (PITX1) on chromosome 5q31: a candidate gene analysis. Philippi A, et al. BMC Med Genet, 2007 Dec 6. PMID 18053270.
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