TOX3 Antibody (N-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | O15405 |
Other Accession | NP_001073899.1, 27324, 244579 (mouse), 291908 (rat) |
Predicted | Human, Mouse, Rat |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 63342 Da |
Gene ID | 27324 |
---|---|
Other Names | TOX high mobility group box family member 3, CAG trinucleotide repeat-containing gene F9 protein, Trinucleotide repeat-containing gene 9 protein, TOX3, CAGF9, TNRC9 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TOX3 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TOX3 |
---|---|
Synonyms | CAGF9, TNRC9 |
Function | Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen- responsive C3 promoter region. |
Cellular Location | Nucleus. |
Tissue Location | Expressed mainly in epithelial cells. Expressed in the central nervous system (CNS), in the ileum and within the brain in the frontal and occipital lobe. |
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Provided below are standard protocols that you may find useful for product applications.
References
Genome-wide association study identifies novel breast cancer susceptibility loci. Easton DF et al. Nature. 2007 Jun 28;447(7148):1087-93. PMID: 17529967
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