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Formyl Peptide Receptor-like 2 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | P25089 |
| Other Accession | NP_002021.3, 2359 |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 39965 Da |
| Gene ID | 2359 |
|---|---|
| Other Names | N-formyl peptide receptor 3, FMLP-related receptor II, FMLP-R-II, Formyl peptide receptor-like 2, FPR3, FPRH1, FPRL2 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Formyl Peptide Receptor-like 2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FPR3 |
|---|---|
| Synonyms | FPRH1, FPRL2 |
| Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin (PubMed:15465011). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Detected in various tissues with highest expression in lung. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
F2L, a peptide derived from heme-binding protein, chemoattracts mouse neutrophils by specifically activating Fpr2, the low-affinity N-formylpeptide receptor. Gao JL, Guillabert A, Hu J, Le Y, Urizar E, Seligman E, Fang KJ, Yuan X, Imbault V, Communi D, Wang JM, Parmentier M, Murphy PM, Migeotte I. J Immunol. 2007 Feb 1;178(3):1450-6. PMID: 17237393
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