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UBP1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q9NZI7 |
| Other Accession | NP_055332.3, NP_001121632.1, 7342, 22221 (mouse), 301038 (rat) |
| Predicted | Human, Mouse, Rat, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 60491 Da |
| Gene ID | 7342 |
|---|---|
| Other Names | Upstream-binding protein 1, Transcription factor LBP-1, UBP1, LBP1 |
| Dilution | E~~N/A |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UBP1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBP1 |
|---|---|
| Synonyms | LBP1 |
| Function | Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA- box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep- G2 and HeLa cell lines. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Reported variants represent identical protein: NP_001121633.1, NP_055332.3.
References
LBP-1b, LBP-9, and LBP-32/MGR detected in syncytiotrophoblasts from first-trimester human placental tissue and their transcriptional regulation. Henderson YC, Frederick MJ, Wang MT, Hollier LM, Clayman GL, DNA and cell biology 2008 Feb 27 (2): 71-9. PMID: 18004979
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