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ANTXR2 / CMG2 Antibody (internal regoin)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC, E |
|---|---|
| Primary Accession | P58335 |
| Other Accession | NP_477520.2, NP_001139266.1, 118429 |
| Reactivity | Human, Mouse, Rat |
| Predicted | Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 53666 Da |
| Gene ID | 118429 |
|---|---|
| Other Names | Anthrax toxin receptor 2, Capillary morphogenesis gene 2 protein, CMG-2, ANTXR2, CMG2 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ANTXR2 / CMG2 Antibody (internal regoin) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ANTXR2 (HGNC:21732) |
|---|---|
| Function | Necessary for cellular interactions with laminin and the extracellular matrix. |
| Cellular Location | [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Note=Expressed at the cell surface [Isoform 3]: Secreted. |
| Tissue Location | Expressed in prostate, thymus, ovary, testis, pancreas, colon, heart, kidney, lung, liver, peripheral blood leukocytes, placenta, skeletal muscle, small intestine and spleen |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize both reported isoforms (NP_477520.2; NP_001139266.1).
References
Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum. Deuquet J, Abrami L, Difeo A, Ramirez MC, Martignetti JA, van der Goot FG, Human mutation 2009 Apr 30 (4): 583-9. PMID: 19191226
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