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POU2F3 Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - POU2F3 Antibody (internal region) AF3198a
    AF3198a (2 µg/ml) staining of HEK293 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UKI9
Other Accession NP_055167.2, 25833
Reactivity Human
Predicted Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 47432 Da
Additional Information
Gene ID 25833
Other Names POU domain, class 2, transcription factor 3, Octamer-binding protein 11, Oct-11, Octamer-binding transcription factor 11, OTF-11, Transcription factor PLA-1, Transcription factor Skn-1, POU2F3, OTF11, PLA1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPOU2F3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name POU2F3 (HGNC:19864)
Synonyms OTF11, PLA1
Function Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3') and regulates cell type-specific differentiation pathways. Involved in the regulation of keratinocytes differentiation (PubMed:11329378). The POU2F3-POU2AF2/POU2AF3 complex drives the expression of tuft-cell-specific genes, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues (PubMed:35576971).
Cellular Location Nucleus {ECO:0000250|UniProtKB:P31362}.
Tissue Location Specifically expressed in epidermis and cultured keratinocytes.
Research Areas
Citations (0)
citation

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References

Transcription factor human Skn-1a enhances replication of human papillomavirus DNA through the direct binding to two sites near the viral replication origin. Kukimoto I, Mori S, Sato H, Takeuchi T, Kanda T, The FEBS journal 2008 Jun 275 (12): 3123-35. PMID: 18479461

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$ 341.00
Cat# AF3198a
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