Goat anti-AADAT (int.) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC, Pep-ELISA |
---|---|
Primary Accession | Q8N5Z0 |
Other Accession | NP_057312.1, NP_872603.1 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Clone Names | AADAT |
Calculated MW | 47352 Da |
Gene ID | 51166 |
---|---|
Other Names | AADAT; aminoadipate aminotransferase; KAT2; KATII; L kynurenine/alpha aminoadipate aminotransferase; L-kynurenine/alpha-aminoadipate aminotransferase; alpha-aminoadipate aminotransferase; kynurenine aminotransferase II |
Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Immunogen | Both reported variants represent identical protein (NP_057312.1 and NP_872603.1). |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat anti-AADAT (int.) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AADAT (HGNC:17929) |
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Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). |
Cellular Location | Mitochondrion. |
Tissue Location | Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary |
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