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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > Goat anti-AIF1 / IBA1 (isoform 1 and 3), biotinylated Antibody
Goat anti-AIF1 / IBA1 (isoform 1 and 3), biotinylated Antibody
Peptide-affinity purified goat antibody
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Application 
| WB, Pep-ELISA |
|---|---|
| Primary Accession | P55008 |
| Other Accession | NP_116573.1, NP_004838.1, NP_001614.3 |
| Reactivity | Human, Mouse, Rat, Pig |
| Host | Goat |
| Clonality | Polyclonal |
| Clone Names | AIF1 |
| Calculated MW | 16703 Da |
| Gene ID | 199 |
|---|---|
| Other Names | AIF1; allograft inflammatory factor 1; AIF-1; IBA1; IRT-1; IRT1; allograft inflammatory factor-1 splice variant Hara-1; interferon gamma responsive transcript; ionized calcium-binding adapter molecule 1; protein G1 |
| Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Immunogen | This antibody is expected to recognize isoform 1 (NP_116573.1) and isoform 3 (NP_001614.3). |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Goat anti-AIF1 / IBA1 (isoform 1 and 3), biotinylated Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AIF1 |
|---|---|
| Synonyms | G1, IBA1 |
| Function | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
| Cellular Location | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:O70200}. Cell projection, ruffle membrane {ECO:0000250|UniProtKB:O70200}; Peripheral membrane protein {ECO:0000250|UniProtKB:O70200}; Cytoplasmic side {ECO:0000250|UniProtKB:O70200}. Cell projection, phagocytic cup {ECO:0000250|UniProtKB:O70200}. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis {ECO:0000250|UniProtKB:O70200} |
| Tissue Location | Detected in T-lymphocytes and peripheral blood mononuclear cells. |
Research Areas
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$ 341.00
Cat# AF4347a
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