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Goat anti-OCIL Antibody

Peptide-affinity purified goat antibody

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, FC, Pep-ELISA
Primary Accession Q9UHP7
Other Accession NP_037401.1, NP_001004419.1, NP_001184246.1
Reactivity Human, Dog, Bovine
Host Goat
Clonality Polyclonal
Clone Names CLEC2D
Calculated MW 21849 Da
Additional Information
Gene ID 29121
Other Names CLEC2D; C-type lectin domain family 2, member D; CLAX; LLT1; OCIL; C-type lectin related f; C-type lectin superfamily 2, member D; lectin-like NK cell receptor; lectin-like transcript 1; osteoclast inhibitory lectin
Format Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Immunogen This antibody is expected to recognize all isoforms (NP_037401.1; NP_001004419.1; NP_001184246.1).
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat anti-OCIL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLEC2D
Synonyms CLAX, LLT1, OCIL
Function Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis (PubMed:20843815, PubMed:16339513). Inhibits osteoclast formation (PubMed:14753741, PubMed:15123656). Inhibits bone resorption (PubMed:14753741). Modulates the release of interferon-gamma (PubMed:15104121). Binds high molecular weight sulfated glycosaminoglycans (PubMed:15123656).
Cellular Location Cell membrane; Single-pass type II membrane protein [Isoform 4]: Endoplasmic reticulum
Tissue Location Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells.
Research Areas
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$ 341.00
Cat# AF4513a
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