KD-Validated Anti-C4BPB Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, ICC |
|---|---|
| Primary Accession | P20851 |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB5940 |
| Calculated MW | Predicted, 28 kDa, observed, 42 kDa |
| Gene Name | C4BPB |
| Aliases | C4BPB; Complement Component 4 Binding Protein Beta; C4b-Binding Protein Beta Chain; C4BP; Complement Component 4 Binding Protein, Beta Chain; Complement Component 4-Binding Protein, Beta; C4b Binding Protein, Beta Chain |
| Immunogen | A synthesized peptide derived from human C4 binding protein |
| Gene ID | 725 |
|---|---|
| Other Names | C4b-binding protein beta chain, C4BPB |
| Name | C4BPB |
|---|---|
| Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S. |
| Cellular Location | Secreted. |

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