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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-IDH1 Rabbit Monoclonal Antibody
KD-Validated Anti-IDH1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | O75874 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 2105 |
| Calculated MW | Predicted, 47 kDa , observed, 45 kDa |
| Gene Name | IDH1 |
| Aliases | IDH1; Isocitrate Dehydrogenase (NADP(+)) 1; Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic; Isocitrate Dehydrogenase 1 (NADP+), Soluble; Isocitrate Dehydrogenase [NADP] Cytoplasmic; Oxalosuccinate Decarboxylase; NADP(+)-Specific ICDH; EC 1.1.1.42; PICD; IDH; NADP-Dependent Isocitrate Dehydrogenase, Peroxisomal; NADP-Dependent Isocitrate Dehydrogenase, Cytosolic; Epididymis Secretory Sperm Binding Protein; Cytosolic NADP-Isocitrate Dehydrogenase; Isocitrate Dehydrogenase 1 (NADP+); Epididymis Secretory Protein Li 26; Epididymis Luminal Protein 216; HEL-S-26; HEL-216; IDCD; IDPC; IDPc; IDP |
| Immunogen | A synthesized peptide derived from human IDH1 |
| Gene ID | 3417 |
|---|---|
| Other Names | Isocitrate dehydrogenase [NADP] cytoplasmic, IDH, IDH1, 1.1.1.42, Cytosolic NADP-isocitrate dehydrogenase, IDPc, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase, IDH1, PICD |
| Name | IDH1 |
|---|---|
| Synonyms | PICD |
| Function | Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (PubMed:10521434, PubMed:19935646). Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (PubMed:10521434). May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity). |
| Cellular Location | Cytoplasm, cytosol. Peroxisome |
Research Areas
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Application Protocols
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$ 149.00
$ 499.00
Cat# AGI1060
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