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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-RAC3 Rabbit Monoclonal Antibody
KD-Validated Anti-RAC3 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P60763 |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 2175 |
| Calculated MW | Predicted, 21 kDa, observed, 21 kDa |
| Gene Name | RAC3 |
| Aliases | RAC3; Rac Family Small GTPase 3; Ras-Related C3 Botulinum Toxin Substrate 3 (Rho Family, Small GTP Binding Protein Rac3); Ras-Related C3 Botulinum Toxin Substrate 3; P21-Rac3; Rho Family, Small GTP Binding Protein Rac3; EC 3.6.5.2 |
| Immunogen | A synthesized peptide derived from human RAC3 |
| Gene ID | 5881 |
|---|---|
| Other Names | Ras-related C3 botulinum toxin substrate 3, 3.6.5.2, p21-Rac3, RAC3 (HGNC:9803) |
| Name | RAC3 (HGNC:9803) |
|---|---|
| Function | Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner. |
| Cellular Location | Cytoplasm. Endomembrane system. Cell projection, lamellipodium. Cytoplasm, perinuclear region. Cell membrane. Cytoplasm, cytoskeleton. Note=Membrane-associated when activated. Colocalizes with NRBP to endomembranes and at the cell periphery in lamellipodia Colocalized with CIB1 in the perinuclear area and at the cell periphery |
| Tissue Location | Highest levels in brain, also detected in heart, placenta and pancreas |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 149.00
$ 499.00
Cat# AGI1077
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