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KD-Validated Anti-Mannose Receptor (CD206) Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

     
  • WB - KD-Validated Anti-Mannose Receptor (CD206) Rabbit Monoclonal Antibody AGI1126
    Western blotting analysis using anti-mannose receptor (CD206) antibody (Cat#61279). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-mannose receptor (CD206) antibody (Cat#61279, 1:5,000) and HRP-conjugated goat anti rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).
    detail
  • WB - KD-Validated Anti-Mannose Receptor (CD206) Rabbit Monoclonal Antibody AGI1126
    Western blotting analysis using anti-mannose receptor (CD206) antibody (Cat#61279). Mannose receptor (CD206) expression in wild-type (WT) and MRC1 knockdown (KD) HeLa cells with 20 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-mannose receptor (CD206) antibody (Cat#61279, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).
    detail
  • FC - KD-Validated Anti-Mannose Receptor (CD206) Rabbit Monoclonal Antibody AGI1126
    Flow cytometric analysis of Mannose Receptor (CD206) expression in HepG2 cells using Mannose Receptor (CD206) antibody (Cat#61279, 1:2,000). Green, isotype control; red, Mannose Receptor (CD206).
    detail
  • ICC - KD-Validated Anti-Mannose Receptor (CD206) Rabbit Monoclonal Antibody AGI1126
    lmmunocytochemical staining of HepG2 cells with Mannose Receptor (CD206) antibody (Cat#61279, 1:1,000). Nuclei were stained blue with DAPl; Mannose Receptor (CD206) was stained magenta with Alexa Fluor® 647. lmages were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: High. Scale bar, 20 µm.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC, ICC
Primary Accession P22897
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Isotype Rabbit IgG
Clone Names 25GB2060
Calculated MW Predicted, 166 kDa; observed, 166 kDa
Gene Name MRC1
Aliases MRC1; Mannose Receptor C-Type 1; CLEC13DL; CLEC13D; BA541I19.1; MRC1L1; CD206; Macrophage Mannose Receptor 1-Like Protein 1; C-Type Lectin Domain Family 13 Member D; Mannose Receptor, C Type 1-Like 1; Macrophage Mannose Receptor ; Human Mannose Receptor; MMR; HMR; C-Type Lectin Domain Family 13 Member D-Like; Macrophage Mannose Receptor; Mannose Receptor, C Type 1; CD206 Antigen
Immunogen A synthesized peptide derived from human MRC1
Additional Information
Gene ID 4360
Other Names Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Human mannose receptor, hMR, Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1
Protein Information
Name MRC1
Synonyms CLEC13D, CLEC13DL, MRC1L1
Function Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. (Microbial infection) Acts as a receptor for Dengue virus envelope protein E.
Cellular Location Endosome membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)
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$ 149.00
$ 499.00
Cat# AGI1126
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