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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-CDC16 Rabbit Monoclonal Antibody
KD-Validated Anti-CDC16 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | Q13042 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB 3415 |
| Calculated MW | Predicted, 72 kDa , observed, 72 kDa |
| Gene Name | CDC16 |
| Aliases | CDC16; Cell Division Cycle 16; ANAPC6; APC6; CUT9; Cell Division Cycle Protein 16 Homolog; Anaphase-Promoting Complex, Subunit 6; Cyclosome Subunit 6; CDC16Hs; CDC16 (Cell Division Cycle 16, S. Cerevisiae, Homolog); CDC16 Cell Division Cycle 16 Homolog (S. Cerevisiae); Cell Division Cycle 16 Homolog (S. Cerevisiae); Anaphase-Promoting Complex Subunit 6; Cell Division Cycle 16 Homolog; CDC16 Homolog |
| Immunogen | A synthesized peptide derived from human Cdc16/APC6 |
| Gene ID | 8881 |
|---|---|
| Other Names | Cell division cycle protein 16 homolog, Anaphase-promoting complex subunit 6, APC6, CDC16 homolog, CDC16Hs, Cyclosome subunit 6, CDC16, ANAPC6 |
| Name | CDC16 |
|---|---|
| Synonyms | ANAPC6 |
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle (PubMed:18485873). The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (PubMed:18485873). The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins (PubMed:29033132). |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle. |
Research Areas
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Application Protocols
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$ 149.00
$ 499.00
Cat# AGI1185
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