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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-Dihydrofolate reductase Rabbit Monoclonal Antibody
KD-Validated Anti-Dihydrofolate reductase Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, ICC |
|---|---|
| Primary Accession | P00374 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB3575 |
| Calculated MW | Predicted, 21 kDa, observed, 18 kDa |
| Gene Name | DHFR |
| Aliases | DHFR; Dihydrofolate Reductase; DHFR1; EC 1.5.1.3; DHFRP1; DYR |
| Immunogen | A synthesized peptide derived from human DHFR |
| Gene ID | 1719 |
|---|---|
| Other Names | Dihydrofolate reductase, 1.5.1.3, DHFR |
| Name | DHFR |
|---|---|
| Function | Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2. |
| Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:P00375}. Cytoplasm {ECO:0000250|UniProtKB:P00375} |
| Tissue Location | Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood Expression is higher in the adult brain than in the fetal brain |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 149.00
$ 499.00
Cat# AGI1194
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