KD-Validated Anti-Paired box 6 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, ICC |
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Primary Accession | P26367 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 23GB 2875 |
Calculated MW | Predicted, 47 kDa , observed, 47 kDa |
Gene Name | PAX6 |
Aliases | Paired Box 6; D11S812E; WAGR; AN2; AN; Paired Box Protein Pax-6; Aniridia Type II Protein; Oculorhombin; Aniridia 1; Aniridia 2; AN1; Paired Box Gene 6 (Aniridia, Keratitis); Paired Box 6 PAX6A-ASdel6-AS7 Isoform; Paired Box 6 PAX6A-ASdel6 Isoform; Paired Box 6 PAX6B-ASdel6 Isoform; Paired Box 6 PAX6A-Del6 Isoform; Paired Box 6 PAX6-12a Isoform; Paired Box 6 PAX6D Isoform; Paired Box Homeotic Gene-6; Alternative Protein PAX6; Aniridia, Keratitis; ASGD5; FVH1; MGDA; |
Immunogen | A synthesized peptide derived from human PAX6 |
Gene ID | 5080 |
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Other Names | Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2 |
Name | PAX6 |
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Synonyms | AN2 |
Function | Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Acts as a transcriptional repressor of NFATC1- mediated gene expression (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250|UniProtKB:P63016} |
Tissue Location | [Isoform 1]: Expressed in lymphoblasts. |

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