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> home > Products > Primary Antibodies > Antibody Collections > Prostate negative > KD-Validated Anti-Glutamic-oxaloacetic transaminase 1 Rabbit Monoclonal Antibody
KD-Validated Anti-Glutamic-oxaloacetic transaminase 1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | P17174 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 23GB5585 |
| Calculated MW | Predicted, 46 kDa , observed, 47 kDa |
| Gene Name | GOT1 |
| Aliases | GOT1; Glutamic-Oxaloacetic Transaminase 1; Glutamate Oxaloacetate Transaminase 1; AST1; SGOT; AST; Glutamic-Oxaloacetic Transaminase 1, Soluble; Aspartate Aminotransferase, Cytoplasmic; Cysteine Aminotransferase, Cytoplasmic; Cysteine Transaminase, Cytoplasmic; Aspartate Aminotransferase 1; Aspartate Transaminase 1; Transaminase A; EC 2.6.1.1; CAspAT; CCAT; Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1); Testis Secretory Sperm-Binding Protein Li 196a; Growth-Inhibiting Protein 18; EC 2.6.1.3; ASTQTL1; GIG18 |
| Immunogen | A synthesized peptide derived from human Aspartate Aminotransferase |
| Gene ID | 2805 |
|---|---|
| Other Names | Aspartate aminotransferase, cytoplasmic, cAspAT, 2.6.1.1, 2.6.1.3, Cysteine aminotransferase, cytoplasmic, Cysteine transaminase, cytoplasmic, cCAT, Glutamate oxaloacetate transaminase 1, Transaminase A, GOT1 (HGNC:4432) |
| Name | GOT1 (HGNC:4432) |
|---|---|
| Function | Biosynthesis of L-glutamate from L-aspartate or L-cysteine (PubMed:21900944). Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain. In addition, catalyzes (2S)-2- aminobutanoate, a by-product in the cysteine biosynthesis pathway (PubMed:27827456). |
| Cellular Location | Cytoplasm. |
Research Areas
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$ 399.20
$ 149.00
Cat# AGI1528
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