KD-Validated Anti-Glucose 6 phosphate isomerase Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC |
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Primary Accession | P06744 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 23GB5595 |
Calculated MW | Predicted, 63 kDa , observed, 63 kDa |
Gene Name | GPI |
Aliases | GPI; Glucose-6-Phosphate Isomerase; AMF; NLK; Autocrine Motility Factor; Phosphoglucose Isomerase; Phosphohexose Isomerase; Neuroleukin; EC 5.3.1.9; SA-36; PGI; PHI; Hexose Monophosphate Isomerase; Glucose Phosphate Isomerase; Hexosephosphate Isomerase; Phosphosaccharomutase; Phosphohexomutase; Sperm Antigen-36; Sperm Antigen 36; Oxoisomerase; GNPI; SA36 |
Immunogen | A synthesized peptide derived from human Glucose 6 phosphate isomerase |
Gene ID | 2821 |
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Other Names | Glucose-6-phosphate isomerase, GPI, 5.3.1.9, Autocrine motility factor, AMF, Neuroleukin, NLK, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI, Sperm antigen 36, SA-36, GPI {ECO:0000303|PubMed:2387591, ECO:0000312|HGNC:HGNC:4458} |
Name | GPI {ECO:0000303|PubMed:2387591, ECO:0000312|HGNC:HGNC:4458} |
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Function | In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (PubMed:28803808). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility (PubMed:11437381). Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons (PubMed:11004567, PubMed:3352745). It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (PubMed:11004567, PubMed:3352745). |
Cellular Location | Cytoplasm. Secreted |

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