KD-Validated Anti-SDHC Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, ICC |
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Primary Accession | Q99643 |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 24GB1075 |
Calculated MW | Predicted, 18 kDa , observed , 12 kDa |
Gene Name | SDHC |
Aliases | Succinate Dehydrogenase Complex Subunit C; CYB560; CybL; Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kD; Succinate Dehydrogenase Cytochrome B560 Subunit, Mitochondrial; Succinate-Ubiquinone Oxidoreductase Cytochrome B Large Subunit; Succinate Dehydrgenase Cytochrome B; Large Subunit Of Cytochrome B; PGL3; SDH3; Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa; Succinate Dehydrogenase Complex Subunit C Integral Membrane Protein 15kDa; Succinate Dehydrogenase 3, Integral Membrane Subunit; Succinate Dehydrogenase Cytochrome B560 Subunit; Cytochrome B Large Subunit Of Complex II; Integral Membrane Protein CII-3b; Integral Membrane Protein CII-3; PPGL3; QPs-1; QPS1; QPs1; CYBL |
Immunogen | A synthesized peptide derived from human SDHC |
Gene ID | 6391 |
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Other Names | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial, Integral membrane protein CII-3, Malate dehydrogenase [quinone] cytochrome b560 subunit, QPs-1, QPs1, Succinate dehydrogenase complex subunit C, Succinate-ubiquinone oxidoreductase cytochrome B large subunit, CYBL, SDHC, CYB560, SDH3 |
Name | SDHC |
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Synonyms | CYB560, SDH3 |
Function | Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:9533030). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto- oxaloacetate (By similarity). |
Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |

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