KD-Validated Anti-RAD23A Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, ICC |
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Primary Accession | P54725 |
Reactivity | Human, Mouse |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 24GB1080 |
Calculated MW | Predicted, 40 kDa , observed , 55 kDa |
Gene Name | RAD23A |
Aliases | RAD23 Homolog A, Nucleotide Excision Repair Protein; HHR23A; UV Excision Repair Protein RAD23 Homolog A; RAD23, Yeast Homolog, A; MGC111083; HR23A; RAD23 (S. Cerevisiae) Homolog A; RAD23 Homolog A (S. Cerevisiae) |
Immunogen | A synthesized peptide derived from human RAD23A |
Gene ID | 5886 |
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Other Names | UV excision repair protein RAD23 homolog A, HR23A, hHR23A, RAD23A |
Name | RAD23A |
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Function | Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'- linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. (Microbial infection) Involved in Vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 Vpr with the host proteasome. |
Cellular Location | Nucleus. |

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