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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-TNF Alpha Induced Protein 8 Rabbit Monoclonal Antibody
KD-Validated Anti-TNF Alpha Induced Protein 8 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC |
|---|---|
| Primary Accession | O95379 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 24GB2315 |
| Calculated MW | Predicted, 23 kDa , observed , 18,21 kDa |
| Gene Name | TNFAIP8 |
| Aliases | TNFAIP8; TNF Alpha Induced Protein 8; MDC-3.13; SCC-S2; GG2-1; Head And Neck Tumor And Metastasis-Related Protein; Tumor Necrosis Factor Alpha-Induced Protein 8; NF-Kappa-B-Inducible DED-Containing Protein; TNF-Induced Protein GG2-1; NDED; Tumor Necrosis Factor, Alpha-Induced Protein 8; Tumor Necrosis Factor, Alpha Induced Protein 8; TNF Alpha-Induced Protein 8; SCCS2 |
| Immunogen | A synthesized peptide derived from human TNFAIP8 |
| Gene ID | 25816 |
|---|---|
| Other Names | Tumor necrosis factor alpha-induced protein 8, TNF alpha-induced protein 8, Head and neck tumor and metastasis-related protein, MDC-3.13, NF-kappa-B-inducible DED-containing protein, NDED, SCC-S2, TNF-induced protein GG2-1, TNFAIP8 |
| Name | TNFAIP8 |
|---|---|
| Function | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle |
Research Areas
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Application Protocols
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$ 149.00
$ 499.00
Cat# AGI1726
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