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> home > Products > Primary Antibodies > Antibody Collections > KD-Validated Antibodies > KD-Validated Anti-CNDP2 Mouse Monoclonal Antibody
KD-Validated Anti-CNDP2 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q96KP4 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB7930 |
| Calculated MW | Predicted, 53 kDa, observed, 53 kDa |
| Gene Name | CNDP2 |
| Aliases | CNDP2; Carnosine Dipeptidase 2; CPGL; CN2; Peptidase A; HsT2298; PEPA; CNDP Dipeptidase 2 (Metallopeptidase M20 Family); Glutamate Carboxypeptidase-Like Protein 1; Cytosolic Non-Specific Dipeptidase; Cytosolic Nonspecific Dipeptidase; Carnosine Dipeptidase II; Threonyl Dipeptidase; Carnosinase-2; FLJ10830; HEL-S-13; Epididymis Secretory Protein Li 13; CNDP Dipeptidase; EC 3.4.13.18 |
| Immunogen | Recombinant protein of human CNDP2 |
| Gene ID | 55748 |
|---|---|
| Other Names | Cytosolic non-specific dipeptidase, 3.4.13.18, CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, Threonyl dipeptidase, CNDP2 {ECO:0000303|PubMed:25964343, ECO:0000312|HGNC:HGNC:24437} |
| Name | CNDP2 {ECO:0000303|PubMed:25964343, ECO:0000312|HGNC:HGNC:24437} |
|---|---|
| Function | Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides (By similarity). Mediates threonyl dipeptide catabolism in a tissue- specific way (By similarity). Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism (PubMed:12473676, PubMed:19346245). Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis (PubMed:25964343). Plays a role in the regulation of cell cycle arrest and apoptosis (PubMed:17121880, PubMed:24395568). |
| Cellular Location | Cytoplasm |
| Tissue Location | [Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568). |
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$ 149.00
$ 499.00
Cat# AGI2009
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