KD-Validated Anti-CBX8 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC |
---|---|
Primary Accession | Q9HC52 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG2b |
Clone Names | 24GB7980 |
Calculated MW | Predicted, 43 kDa, observed, 43 kDa |
Gene Name | CBX8 |
Aliases | CBX8; Chromobox 8; RC1; PC3; Chromobox Protein Homolog 8; Rectachrome 1; Polycomb 3; HPC3; Chromobox Homolog 8 (Pc Class Homolog, Drosophila); Chromobox Homolog 8 (Drosophila Pc Class); Pc Class 3 Homolog (Drosophila); Chromobox Homolog 8; Pc Class 3 Homolog; Polycomb 3 Homolog; HPc3; Pc3 |
Immunogen | Recombinant protein of human CBX8 |
Gene ID | 57332 |
---|---|
Other Names | Chromobox protein homolog 8, Polycomb 3 homolog, Pc3, hPc3, Rectachrome 1, CBX8, PC3, RC1 |
Name | CBX8 |
---|---|
Synonyms | PC3, RC1 |
Function | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
Cellular Location | Nucleus. |

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