KD-Validated Anti-EPHX1 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | P07099 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG2b |
Clone Names | 24GB8225 |
Calculated MW | Predicted, 53 kDa, observed, 48 kDa |
Gene Name | EPHX1 |
Aliases | EPHX1; Epoxide Hydrolase 1; EPHX; Epoxide Hydrolase 1, Microsomal (Xenobiotic); Epoxide Hydratase; EPOX; MEH; Epoxide Hydrolase 1 Microsomal; Microsomal Epoxide Hydrolase; EC 3.3.2.9; HYL1 |
Immunogen | Recombinant protein of human EPHX1 |
Gene ID | 2052 |
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Other Names | Epoxide hydrolase 1, 3.3.2.9, EPHX1 (HGNC:3401), EPHX, EPOX |
Name | EPHX1 (HGNC:3401) |
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Synonyms | EPHX, EPOX |
Function | Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water (By similarity). Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids (PubMed:22798687). Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol (PubMed:24958911). Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity). |
Cellular Location | Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P07687}; Single-pass type III membrane protein {ECO:0000250|UniProtKB:P07687} |
Tissue Location | Found in liver.. |

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