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KD-Validated Anti-HMMR Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

     
  • WB - KD-Validated Anti-HMMR Rabbit Monoclonal Antibody AGI2100
    Western blotting analysis using anti-CD168 antibody (Cat#64888). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-CD168 antibody (Cat#64888, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).
    detail
  • WB - KD-Validated Anti-HMMR Rabbit Monoclonal Antibody AGI2100
    Western blotting analysis using anti-CD168 antibody (Cat#64888). CD168 expression in wild-type (WT) and HMMR knockdown (KD) HSHC cells with 20 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-CD168 antibody (Cat#64888, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).
    detail
  • FC - KD-Validated Anti-HMMR Rabbit Monoclonal Antibody AGI2100
    Flow cytometric analysis of BNIP3 expression in HepG2 cells using anti-BNIP3 antibody (Cat# 64885, 1:1,000). Green, isotype control; red, BNIP3.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, FC
Primary Accession O75330
Reactivity Human
Clonality Monoclonal
Isotype Rabbit IgG
Clone Names 24GB13600
Calculated MW Predicted, 84 kDa, observed, 75 kDa
Gene Name HMMR
Aliases HMMR; Hyaluronan Mediated Motility Receptor; RHAMM; CD168; Intracellular Hyaluronic Acid-Binding Protein; Receptor For Hyaluronan-Mediated Motility; IHABP; Hyaluronan-Mediated Motility Receptor (RHAMM); Hyaluronan-Mediated Motility Receptor; CD168 Antigen
Immunogen A synthesized peptide derived from human CD168
Additional Information
Gene ID 3161
Other Names Hyaluronan mediated motility receptor, Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168, HMMR, IHABP, RHAMM
Protein Information
Name HMMR
Synonyms IHABP, RHAMM
Function Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity).
Cellular Location Cell surface {ECO:0000250|UniProtKB:Q00547}. Cytoplasm. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q00547}
Tissue Location Expressed in testis (PubMed:22965910). Expressed in the breast (PubMed:8890751).
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2100
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