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> home > Products > Primary Antibodies > Antibody Collections > Thyroid gland positive > KD-Validated Anti-RBBP7 Mouse Monoclonal Antibody
KD-Validated Anti-RBBP7 Mouse Monoclonal Antibody
Mouse monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q16576 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1 |
| Clone Names | 24GB13975 |
| Calculated MW | Predicted, 48 kDa, observed, 50 kDa |
| Gene Name | RBBP7 |
| Aliases | RBBP7; RB Binding Protein 7, Chromatin Remodeling Factor; Histone Acetyltransferase Type B Subunit 2; Retinoblastoma-Binding Protein P46; Retinoblastoma-Binding Protein 7; RbAp46; G1/S Transition Control Protein-Binding Protein RbAp46; Nucleosome-Remodeling Factor Subunit RBAP46; Retinoblastoma-Binding Protein RbAp46; Histone-Binding Protein RBBP7; RBBP-7; Retinoblastoma Binding Protein 7; RB Binding Protein 7; RBAP46 |
| Immunogen | Recombinant protein of human RBBP7 |
| Gene ID | 5931 |
|---|---|
| Other Names | Histone-binding protein RBBP7, Histone acetyltransferase type B subunit 2, Nucleosome-remodeling factor subunit RBAP46, Retinoblastoma-binding protein 7, RBBP-7, Retinoblastoma-binding protein p46, RBBP7, RBAP46 |
| Name | RBBP7 |
|---|---|
| Synonyms | RBAP46 |
| Function | Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex. |
| Cellular Location | Nucleus |
Research Areas
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$ 149.00
$ 499.00
Cat# AGI2165
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