KD-Validated Anti-SELENBP1 Mouse Monoclonal Antibody
Mouse monoclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q13228 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG2a |
Clone Names | 24GB13995 |
Calculated MW | Predicted, 52 kDa, observed, 50 kDa |
Gene Name | SELENBP1 |
Aliases | SELENBP1; Selenium Binding Protein 1; Methanethiol Oxidase; HSBP; LPSB; 56 KDa Selenium-Binding Protein; HSP56; SBP56; SP56; MTO; Epididymis Secretory Sperm Binding Protein Li 134P; Selenium-Binding Protein 1; HEL-S-134P; EC 1.8.3.4; EHMTO; SBP |
Immunogen | Recombinant protein of human SELENB1 |
Gene ID | 8991 |
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Other Names | Methanethiol oxidase, MTO, 1.8.3.4, 56 kDa selenium-binding protein, SBP56, SP56, Selenium-binding protein 1, SELENBP1, SBP |
Name | SELENBP1 |
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Synonyms | SBP |
Function | Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria (PubMed:29255262). Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity). |
Cellular Location | Nucleus. Cytoplasm, cytosol Membrane {ECO:0000250|UniProtKB:Q8VIF7}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q8VIF7}. Note=May associate with Golgi membrane (By similarity). May associate with the membrane of autophagosomes (By similarity). {ECO:0000250|UniProtKB:Q8VIF7} |
Tissue Location | Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. |

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