KD-Validated Anti-MARS1 Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, ICC |
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Primary Accession | P56192 |
Reactivity | Rat, Human |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 25GB185 |
Calculated MW | Predicted, 101 kDa; observed, 95 kDa |
Gene Name | MARS1 |
Aliases | MARS1; Methionyl-TRNA Synthetase 1; MetRS; Methionine--TRNA Ligase, Cytoplasmic; SPG70; CMT2U; MARS; Methionyl-TRNA Synthetase; EC 6.1.1.10; Methionine TRNA Ligase 1, Cytoplasmic; Cytosolic Methionyl-TRNA Synthetase; ILFS2; MTRNS; ILLD; TTD9; MRS |
Immunogen | A synthesized peptide derived from human MARS |
Gene ID | 4141 |
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Other Names | Methionine--tRNA ligase, cytoplasmic, 6.1.1.10, Methionyl-tRNA synthetase, MetRS, MARS1 (HGNC:6898), MARS |
Name | MARS1 (HGNC:6898) |
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Synonyms | MARS |
Function | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA (PubMed:11714285). Plays a role in the synthesis of ribosomal RNA in the nucleolus (PubMed:10791971). |
Cellular Location | Cytoplasm, cytosol. Nucleus, nucleolus. Note=Localizes to the nucleolus in proliferative cells but disappears in quiescent cells |

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