KD-Validated Anti-PAIP1 Rabbit Monoclonal Antibody
Rabbit monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, FC |
|---|---|
| Primary Accession | Q9H074 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB195 |
| Calculated MW | Predicted, 54 kDa, observed, 45-60 kDa |
| Gene Name | PAIP1 |
| Aliases | PAIP1; Poly(A) Binding Protein Interacting Protein 1; PABP-Interacting Protein 1; Polyadenylate-Binding Protein-Interacting Protein 1; PAIP-1; Poly(A)-Binding Protein-Interacting Protein 1; PABC1-Interacting Protein 1 |
| Immunogen | Recombinant protein of human MTHFR |
| Gene ID | 10605 |
|---|---|
| Other Names | Polyadenylate-binding protein-interacting protein 1, PABP-interacting protein 1, PAIP-1, Poly(A)-binding protein-interacting protein 1, PAIP1 (HGNC:16945) |
| Name | PAIP1 (HGNC:16945) |
|---|---|
| Function | Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA- binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. |
| Cellular Location | Cytoplasm. |

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