KD-Validated Anti-SMYD4 Mouse Monoclonal Antibody
Mouse monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
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Primary Accession | Q8IYR2 |
Reactivity | Human |
Clonality | Monoclonal |
Isotype | Mouse IgG1 |
Clone Names | 25GB4235 |
Calculated MW | Predicted, 89 kDa; observed, 75 kDa |
Gene Name | SMYD4 |
Aliases | SMYD4; SET And MYND Domain Containing 4; KIAA1936; ZMYND21; SET And MYND Domain-Containing Protein 4; EC 2.1.1.- |
Immunogen | Recombinant protein of human SMYD4 |
Gene ID | 114826 |
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Other Names | SET and MYND domain-containing protein 4, 2.1.1.-, SMYD4, KIAA1936 |
Name | SMYD4 (HGNC:21067) |
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Synonyms | KIAA1936 |
Function | Protein-lysine N-methyltransferase. Monomethylates PRMT5, modulating its transcriptional activity (PubMed:38438251). May also act as a histone methyltransferase (By similarity). Plays a critical role in cardiac development. Acts as a key epigenetic regulator of gene expression during cardiac development via its dual activities as a methyltransferase and negative regulator of HDAC1 (By similarity). |
Cellular Location | Nucleus. Cytoplasm |

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