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KD-Validated Anti-TAF1C Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

     
  • WB - KD-Validated Anti-TAF1C Rabbit Monoclonal Antibody AGI2272
    Western blotting analysis using anti-TAF1C antibody (Cat#AGI2272). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-TAF1C antibody (Cat#AGI2272, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody respectively.
    detail
  • WB - KD-Validated Anti-TAF1C Rabbit Monoclonal Antibody AGI2272
    Western blotting analysis using anti-TAF1C antibody (Cat#AGI2272). TAF1C expression in wild-type (WT) and TAF1C shRNA knockdown (KD) HT-1080 cells with 20 µg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-TAF1C antibody (Cat#AGI2272, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody respectively.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q15572
Reactivity Rat, Human
Clonality Monoclonal
Isotype Rabbit IgG
Clone Names 25GB4510
Calculated MW Predicted, 95 kDa; observed, 100 kDa
Gene Name TAF1C
Aliases TAF1C; TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit C; TAFI110; MGC:39976; TAFI95; SL1; TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa; TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kD; TATA Box-Binding Protein-Associated Factor RNA Polymerase I Subunit C; RNA Polymerase I-Specific TBP-Associated Factor 110 KDa; Transcription Initiation Factor SL1/TIF-IB Subunit C; TATA Box-Binding Protein-Associated Factor 1C; TBP-Associated Factor 1C; TATA-Box Binding Protein Associated Factor, RNA Polymerase I, C; Transcription Factor SL1; SL1, 110kD Subunit
Immunogen A synthesized peptide derived from human TAF1C
Additional Information
Gene ID 9013
Other Names TATA box-binding protein-associated factor RNA polymerase I subunit C, RNA polymerase I-specific TBP-associated factor 110 kDa, TAFI110, TATA box-binding protein-associated factor 1C, TBP-associated factor 1C, Transcription initiation factor SL1/TIF-IB subunit C, TAF1C
Protein Information
Name TAF1C
Function Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Cellular Location Nucleus, nucleolus
Research Areas
Citations (0)
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$ 149.00
$ 499.00
Cat# AGI2272
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