KD-Validated Anti-TAF1C Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB |
---|---|
Primary Accession | Q15572 |
Reactivity | Rat, Human |
Clonality | Monoclonal |
Isotype | Rabbit IgG |
Clone Names | 25GB4510 |
Calculated MW | Predicted, 95 kDa; observed, 100 kDa |
Gene Name | TAF1C |
Aliases | TAF1C; TATA-Box Binding Protein Associated Factor, RNA Polymerase I Subunit C; TAFI110; MGC:39976; TAFI95; SL1; TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kDa; TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, C, 110kD; TATA Box-Binding Protein-Associated Factor RNA Polymerase I Subunit C; RNA Polymerase I-Specific TBP-Associated Factor 110 KDa; Transcription Initiation Factor SL1/TIF-IB Subunit C; TATA Box-Binding Protein-Associated Factor 1C; TBP-Associated Factor 1C; TATA-Box Binding Protein Associated Factor, RNA Polymerase I, C; Transcription Factor SL1; SL1, 110kD Subunit |
Immunogen | A synthesized peptide derived from human TAF1C |
Gene ID | 9013 |
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Other Names | TATA box-binding protein-associated factor RNA polymerase I subunit C, RNA polymerase I-specific TBP-associated factor 110 kDa, TAFI110, TATA box-binding protein-associated factor 1C, TBP-associated factor 1C, Transcription initiation factor SL1/TIF-IB subunit C, TAF1C |
Name | TAF1C |
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Function | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. |
Cellular Location | Nucleus, nucleolus |

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