KD-Validated Anti-SNRPC Rabbit Monoclonal Antibody
Rabbit monoclonal antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB |
|---|---|
| Primary Accession | P09234 |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Isotype | Rabbit IgG |
| Clone Names | 25GB4570 |
| Calculated MW | Predicted, 17 kDa; observed, 19 kDa |
| Gene Name | SNRPC |
| Aliases | SNRPC; Small Nuclear Ribonucleoprotein Polypeptide C; U1-C; Yhc1; U1 Small Nuclear Ribonucleoprotein C; U1 SnRNP C; U1C; U1 Small Nuclear RNP Specific C; U1 SnRNP Protein C |
| Immunogen | A synthesized peptide derived from human SNRPC |
| Gene ID | 6631 |
|---|---|
| Other Names | U1 small nuclear ribonucleoprotein C {ECO:0000255|HAMAP-Rule:MF_03153}, U1 snRNP C {ECO:0000255|HAMAP-Rule:MF_03153}, U1-C {ECO:0000255|HAMAP-Rule:MF_03153}, U1C {ECO:0000255|HAMAP-Rule:MF_03153}, SNRPC {ECO:0000255|HAMAP-Rule:MF_03153} |
| Name | SNRPC {ECO:0000255|HAMAP-Rule:MF_03153} |
|---|---|
| Function | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. |
| Cellular Location | Nucleus {ECO:0000255|HAMAP-Rule:MF_03153, ECO:0000269|PubMed:2136774} |

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