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AADAT antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q8N5Z0 |
| Other Accession | NM_016228, NP_057312 |
| Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Chicken, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 47kDa |
| Gene ID | 51166 |
|---|---|
| Alias Symbol | KAT2, KATII |
| Other Names | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial, KAT/AadAT, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, 2.6.1.39, Alpha-aminoadipate aminotransferase, AadAT, Kynurenine aminotransferase II, Kynurenine--oxoglutarate aminotransferase II, Kynurenine--oxoglutarate transaminase 2, 2.6.1.7, Kynurenine--oxoglutarate transaminase II, AADAT, KAT2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 100 ul of distilled water. Final anti-AADAT antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | AADAT antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AADAT (HGNC:17929) |
|---|---|
| Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). |
| Cellular Location | Mitochondrion. |
| Tissue Location | Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Goh,D.L.,(2002)Mol.Genet.Metab.76(3),172-180ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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