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H1FNT Antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - H1FNT Antibody - C-terminal region AI14273

    Host: Rabbit
    Target Name: H1FNT
    Sample Tissue: Esophagus Tumor lysates
    Antibody Dilution: 1.0μg/ml
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q75WM6
Other Accession NM_181788, NP_861453
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 27kDa
Additional Information
Gene ID 341567
Alias Symbol H1T2
Other Names Testis-specific H1 histone, Haploid germ cell-specific nuclear protein 1, Histone H1t2, H1FNT, HANP1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-H1FNT antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsH1FNT Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name H1-7 (HGNC:24893)
Function Essential for normal spermatogenesis and male fertility (PubMed:16533358). Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single- stranded DNA, ATP and protamine-1.
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q8CJI4}. Chromosome {ECO:0000250|UniProtKB:Q8CJI4}. Note=In round and elongating spermatids, specifically localizes to a chromatin domain at the apical pole. {ECO:0000250|UniProtKB:Q8CJI4}
Tissue Location Testis-specific..
Research Areas
Citations (0)
citation

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References

Huang C.Q.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Scherer S.E.,et al.Nature 440:346-351(2006).
Tanaka H.,et al.Int. J. Androl. 29:353-359(2006).
Martianov I.,et al.Proc. Natl. Acad. Sci. U.S.A. 102:2808-2813(2005).

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$ 389.00
Cat# AI14273
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