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Cxxc5 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q91WA4 |
| Other Accession | NM_133687, NP_598448 |
| Reactivity | Human, Mouse, Rat, Horse, Guinea Pig |
| Predicted | Human, Mouse, Rat, Pig, Horse, Guinea Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 33kDa |
| Gene ID | 67393 |
|---|---|
| Alias Symbol | 4930415K17Rik |
| Other Names | CXXC-type zinc finger protein 5, Cxxc5 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Cxxc5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Cxxc5 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Cxxc5 |
|---|---|
| Function | May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis (By similarity). Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ (By similarity). Binds preferentially to DNA containing cytidine- phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q5XIQ3}. Cytoplasm {ECO:0000250|UniProtKB:Q5XIQ3}. Note=Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane {ECO:0000250|UniProtKB:Q5XIQ3} |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Carninci P.,et al.Science 309:1559-1563(2005).
Andersson T.,et al.J. Biol. Chem. 284:3672-3681(2009).
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$ 389.00
Cat# AI14325
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