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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Rph3a antibody - N-terminal region   

Rph3a antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Rph3a antibody - N-terminal region AI14408

    WB Suggested Anti-Rph3a Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Mouse Muscle
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P47708
Other Accession NM_011286, NP_035416
Reactivity Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 75kDa
Additional Information
Gene ID 19894
Alias Symbol 2900002P20Rik, AU022689, AW108370
Other Names Rabphilin-3A, Exophilin-1, Rph3a
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rph3a antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRph3a antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rph3a
Function Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity). At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP- dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (By similarity). In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Plays also a role in the exocytosis of arginine vasopressin hormone (By similarity).
Cellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:P47709}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:P47709}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250|UniProtKB:P47709}. Membrane {ECO:0000250|UniProtKB:P47709}; Peripheral membrane protein {ECO:0000250|UniProtKB:P47709}
Tissue Location Specifically expressed in brain.
Research Areas
Citations (0)

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References

Inagaki N.,et al.Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
Inagaki N.,et al.J. Biochem. 116:239-242(1994).
Fukuda M.,et al.J. Biol. Chem. 278:15373-15380(2003).
Munton R.P.,et al.Mol. Cell. Proteomics 6:283-293(2007).
Coudevylle N.,et al.J. Biol. Chem. 283:35918-35928(2008).

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$ 389.00
Cat# AI14408
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