|Other Accession||NM_003794, NP_003785|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig|
|Other Names||Sorting nexin-4, SNX4|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SNX4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SNX4 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of endocytosis and in several stages of intracellular trafficking (PubMed:12668730). Plays a role in recycling endocytosed transferrin receptor and prevent its degradation.|
|Cellular Location||Early endosome. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also detected on a juxtanuclear endocytic recycling compartment (ERC)|
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Provided below are standard protocols that you may find useful for product applications.
Haft C.R.,et al.Mol. Cell. Biol. 18:7278-7287(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Traer C.J.,et al.Nat. Cell Biol. 9:1370-1380(2007).
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