|Other Accession||NM_025214, NP_079490|
|Reactivity||Human, Rat, Bovine, Dog|
|Alias Symbol||FLJ25368, SE57-1|
|Other Names||Coiled-coil domain-containing protein 68, Cutaneous T-cell lymphoma-associated antigen se57-1, CTCL-associated antigen se57-1, CCDC68|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CCDC68 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CCDC68 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Centriolar protein required for centriole subdistal appendage assembly and microtubule anchoring in interphase cells (PubMed:28422092). Together with CCDC120, cooperate with subdistal appendage components ODF2, NIN and CEP170 for hierarchical subdistal appendage assembly (PubMed:28422092).|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Localizes to the subdistal appendages of centrioles (PubMed:28422092).|
|Tissue Location||Expressed in bone marrow, colon, small intestine, spleen, testis, trachea and cutaneous T-cell lymphoma (CTCL)|
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Provided below are standard protocols that you may find useful for product applications.
Eichmueller S.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:629-634(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gerhardt A.,et al.Cancer Lett. 208:197-206(2004).
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